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General Description |
Headache, Abdominal pain, Diarrhea, Nausea, Vomiting, Flatulence, Dizziness, Upper respiratory infection, Acid regurgitation, Constipation, Rash, Cough, Bone fracture |
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Side Effects |
Adult: Duodenal Ulcer 20 mg PO once daily for 4-8 weeks Safety and efficacy of omeprazole for maintenance treatment past 1 year not established Helicobacter Pylori Infection Various regimens exist of PPIs combined with antibiotics, 1 example is listed below 20 mg PO q12hr for 10 days, WITH Amoxicillin 1000 mg PO q12hr, AND Clarithromycin 500 mg PO q12hr for 10-14 days Gastric Ulcer 40 mg PO once daily for 4-8 weeks GERD 20 mg PO once daily for 4 weeks Erosive Esophagitis 20 mg PO once daily for 4-8 weeks Maintenance: 20 mg PO once daily for up to 1 year Hypersecretory Condition (eg, Zollinger-Ellison Syndrome) 60 mg PO once daily (initial) up to 360 mg/day divided q8hr PO If dose >80 mg, divide it Pediatric: GERD Indicated for treatment of GERD <1 year: Safety and efficacy not established 5-10 kg: 5 mg PO once daily 10-20 kg: 10 mg PO once daily >20 kg: 20 mg PO once daily Erosive Esophagitis Indicated for treatment and to maintain healing of erosive esophagitis caused by acid-mediated GERD Treatment • <1 month: Safety and efficacy not established • Aged 1 month to <1 year o 3 to <5 kg: 2.5 mg once daily o 5 to <10 kg: 5 mg once daily o ≥10 kg: 10 mg once daily o May treat for up to 6 weeks • Aged 1-16 years o 5 to <10 kg: 5 mg PO once daily o 10 to <20 kg: 10 mg PO once daily o ≥20 kg: 20 mg PO once daily o May treat for 4-8 weeks Maintenance of healing • <1 year: Safety and efficacy not established • ≥1 year: Controlled trials for maintenance do not extend beyond 12 months Neonates (Off-label) Refractory duodenal ulcer or reflux esophagitis: 0.5-1.5 mg/kg PO once daily for up to 8 weeks |
