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Side Effects |
Any medication can cause adverse effects alongside its beneficial therapeutic effects. Consult your physician or pharmacist if you noted any of the below side effects: rash, nausea, diarrhea, vomiting, headache, abdominal pain, anorexia, constipation, dermatitis, dizziness, dry mouth, dyspepsia, fatigue, flatulence, fungal infection, gastritis, genital moniliasis, genital pruritis, hyperglycemia, increased alkaline phosphatase, increased ALT, increased AST, increased creatine phosphokinase, insomnia, leukopenia, pruritus, somnolence, taste perversion, thrombocythemia, urticaria and vaginitis. |
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Direction of use |
DOSAGE AND ADMINISTRATION (adults and adolescents over 18 years of age): – Acute bacterial exacerbation of chronic bronchitis One 320 mg tablet daily for 5 days – Community-acquired pneumonia (of mild to moderate severity) due to known or suspected S. pneumoniae, H. influenzae, M. pneumoniae, or C. pneumoniae infection One 320 mg tablet daily for 5 days – Community-acquired pneumonia (of mild to moderate severity) due to known or suspected multi-drug resistant strains, Klebsiella pneumoniae, and M. catarrhalis. One 320 mg tablet daily for 7 days |
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Warnings |
Modification of the dosage is recommended for patients with creatinine clearance less than 40 mL/min. – Safety and effectiveness of Gemifloxacin has not been established in children and adolescents under 18 years of age. – QT Effects: Fluoroquinolones may prolong the QT interval in some patients. Gemifloxacin should be avoided in patients with a history of prolongation of the QT interval, patients with uncorrected electrolyte disorders (hypokalemia or hypomagnesemia), and in patients receiving Class IA (e.g. Quinidine, procainamide) or Class III (e.g., amiodarone, sotalol) antiarrhythmic agents, as it may lead to an increased risk for ventricular arrhythmias (Torsade de Pointes) – Gemifloxacin should be used with caution in patients with CNS ailments such as epilepsy or patients susceptible to convulsions – Monitor patients for Clostridium Difficile Associated Diarrhea. – Discontinue use immediately in case of tendinitis, tendon rupture, and peripheral neuropathy. – Avoid in patients with known history of myasthenia gravis due to exacerbation of muscle weakness. |
